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Hippocampus CA3 pyramidal GLU cell                                        Show
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CA3 Basket Cell terminals (T)
                
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Intracellular recording from organotypic rat hippocampal cultures have shown that approximately 25% of single spikes in CA3 pyramidal neurons are followed by IPSPs at a fixed latency, presumeably a result of feedback inhibition from inhibitory interneurons. The addition of bicuculline (a competitive GABA(A) antagonist) completely abolished these responses, but they were insensitive to CGP35348, a GABA(B) antagonist                                         Show
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There is also evidence that Zn+ can modulate bicuculline-sensitive responses to GABA early in development in rat (studied less than 8 days old)                                        Show
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