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Neuron
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Neocortex M1 interneuron basket PV GABA cell
Douglas, R, and Martin, K, in Synaptic Organization of the Brain, 4th ed. (Shepherd, GM, ed.). New York: Oxford University Press 1998.
99
 Neuronal Receptors (5)
  
SN Property present CF-Compartment Receptor Connect Note Publication facts
1 Yes Soma Gaba Autaptic self-innervation Autaptic self-innervation of basket cells
2 Yes Proximal equivalent dendrite Gaba Autaptic self-innervation Autaptic self-innervation of basket cells
3 Yes Soma Gaba from other GABAergic interneurons Analysis of synaptic input to layer 4 basket cells show that 79% of symmetric synapses could have originated from other layer 4 basket cells. Soma and proximal dendrites received 76% of all the symmetric synapses
4 Yes Proximal equivalent dendrite Gaba from other GABAergic interneurons GABAergic interneurons (basket cells, dendrite-targeting cells, and double-bouquet cells) form reciprocally interconnected intracortical networks in which basket cells play a prominent role, given the strength of innervation and the proximal placement of synapses by basket cells to their postsynaptic targets
5 Yes Distal equivalent dendrite Glutamate from thalmic afferents, layer 6 pyramidal cells, and spiny stellate cells Dual recording from pyramidal cell-basket cell pairs reveal unitary EPSPs in basket cells mediated by one and two synaptic junctions. The unitary EPSPs have fast rising time and short time duration. Closely timed (10-50 ms) pairs of presynaptic action potentials resulted in statistically significant paired-pulse depression. The reliability of transmission is high, but the fast time course of the EPSPs constrains their temporal summation. Due to the relatively small amplitude of unitary EPSPs several convergent inputs will therefore be required to elicit suprathreshold responses.
 Neuronal Currents (1)
  
SN Property present CF-Compartment Current Connect Note Publication facts
1 Yes Soma I Na,t Anatomical, electrophysiological and molecular diversity of basket cell-like interneurons in layers II-IV of rat somatosensory cortex were studied using patch-clamp electrodes filled with biocytin
 Neuronal Transmitters (3)
  
SN Property present CF-Compartment transmitter Connect Note Publication facts
1 Yes Axon terminal Gaba with spiny neurons (reciprocally) Layer 4 basket cells in cat visual cortex receive excitatory input from neighboring spiny neurons, resulting in large excitatory EPSPs. One third of spiny cell-smooth cell pair were connected reciprocally (postsynaptic targets include local spiny stellate, pyramidal cells, as well as smooth neurons), but the postsynaptic IPSPs evoked by basket cells are slower, GABAergic, probably of GABAA type
2 Yes Axon terminal Gaba Autaptic self-innervation Autaptic self-innervation of basket cells
3 Yes Axon terminal Gaba to other GABAergic interneurons Layer 4 basket cells in cat visual cortex receive excitatory input from neighboring spiny neurons, resulting in large excitatory EPSPs. One third of spiny cell-smooth cell pair were connected reciprocally (postsynaptic targets include local spiny stellate, pyramidal cells, as well as smooth neurons), but the postsynaptic IPSPs evoked by basket cells are slower, GABAergic, probably of GABAA type
Other categories referring to Neocortex M1 interneuron basket PV GABA cell
Neuronal Structure.Neurons   (1)
Revisions: 2
Last Time: 7/3/2017 9:27:10 AM
Reviewer: System Administrator
Owner: System Administrator