OrDB
Neuron
  Data
Spinal cord lumbar motor neuron alpha ACh cell
GM Shepherd, Synaptic Organization of the Brain, New York: Oxford University Press 1979.
177
 Neuronal Receptors (13)
  
SN Property present CF-Compartment Receptor Connect Note Publication facts
1 Yes Soma Gaba ----- GABA from some Renshaw interneurons; IPSPs are Cl- mediated, potentially blocked by picrotoxin
2 Yes Soma Glutamate ----- Glu from Ia axon terminals (reviewed in
3 Yes Soma AMPA Ia afferents release GLU but not LTP or LTD (SOBiv p90).Motoneurons have a high density of AMPA receptors (Vandenberghe et al, JNS 20: 7158, 2000). There is evidence that "glutamate receptor-mediated Ca2+ influx, intracellular Ca2+ accumulation, and subsequent cell death" may be involved in the mechanism of selective motoneuron degeneration in amyotrophic lateral sclerosis.
4 Yes Soma NMDA Ia afferents release GLU but not LTP or LTD (SOBiv p90).Postnatal development and properties of these receptors were studied with whole-cell and outside-out patch-clamp. The conductance and relative distribution were independent of age from postnatal day 4 to 14. The results also suggested that their properties differ from those in spinal cord interneurons
5 Yes Distal equivalent dendrite NMDA Ia afferents release GLU but not LTP or LTD (SOBiv p90).
6 Yes Distal equivalent dendrite AMPA Ia afferents release GLU but not LTP or LTD (SOBiv p90).
7 Yes Middle equivalent dendrite AMPA Ia afferents release GLU but not LTP or LTD (SOBiv p90).
8 Yes Middle equivalent dendrite NMDA Ia afferents release GLU but not LTP or LTD (SOBiv p90).
9 Yes Proximal equivalent dendrite NMDA Ia afferents release GLU but not LTP or LTD (SOBiv p90).
10 Yes Proximal equivalent dendrite Gaba ----- GABA from some Renshaw interneurons; IPSPs are Cl- mediated, potentially blocked by picrotoxin
11 Yes Proximal equivalent dendrite AMPA Ia afferents release GLU but not LTP or LTD (SOBiv p90).
12 Yes Proximal equivalent dendrite Glycine Ia interneurons release GLY SOBiv p94). Ia IPSPs are blocked by strychnine, a known blocker of Glycine receptors (SOBiv p94).
13 Yes Soma Glycine Ia interneurons release GLY SOBiv p94). Ia IPSPs are blocked by strychnine, a known blocker of Glycine receptors (SOBiv p94).
 Neuronal Currents (20)
  
SN Property present CF-Compartment Current Connect Note Publication facts
1 Yes Soma I K,Ca discussed in Burke 1998).
2 Yes Soma I Na,t SOBiv p96).
3 Yes Distal equivalent dendrite I Na,t SOBiv p96).
4 Yes Distal equivalent dendrite I p,q
5 Yes Middle equivalent dendrite I p,q
6 Yes Middle equivalent dendrite I Na,t SOBiv p96).
7 Yes Proximal equivalent dendrite I Na,t SOBiv p96).
8 Yes Proximal equivalent dendrite I p,q
9 Yes Axon hillock I Na,t SOBiv p96).
10 Yes Axon hillock I K
11 Yes Axon fiber I Na,t
12 Yes Axon terminal I N inferred
13 I Calcium Immunohistochemical evidence shows that CaV1.3 is present in soma and all dendritic compartments in turtle motoneurons
14 Yes Distal equivalent dendrite I L high threshold The presence of L-channels in all dendritic compartments in mouse motoneurons is supported by electrophysiology and immunehistochemistry
15 Yes Middle equivalent dendrite I L high threshold The presence of L-channels in all dendritic compartments in mouse motoneurons is supported by electrophysiology and immunehistochemistry
16 Yes Soma I L high threshold Immunohistochemical evidence shows that CaV1.3 (an L type channel; seeMembrane Properties Resource) is present in soma and all dendritic compartments in turtle motoneurons
17 Yes Distal equivalent dendrite I N Electrophysiological evidence shows that N-channels and L-channels are present in all dendritic compartments in turtle motoneurons
18 Yes Middle equivalent dendrite I N Electrophysiological evidence shows that N-channels and L-channels are present in all dendritic compartments in turtle motoneurons
19 Yes Proximal equivalent dendrite I L high threshold The presence of L-channels in all dendritic compartments in mouse motoneurons is supported by electrophysiology and immunehistochemistry
20 Yes Proximal equivalent dendrite I N Electrophysiological evidence shows that N-channels and L-channels are present in all dendritic compartments in turtle motoneurons
 Neuronal Transmitters (1)
  
SN Property present CF-Compartment transmitter Connect Note Publication facts
1 Yes Axon terminal Acetylcholine Skeletal muscle
Other categories referring to Spinal cord lumbar motor neuron alpha ACh cell
Interneurons Connectivity.Principal Neurons   (1)
2 Objects Relationship (edge).Object Two (target)   (1)
Cell Type.NeuronDB Neuron   (1)
Neuronal Structure.Neurons   (1)
Revisions: 11
Last Time: 6/19/2019 12:27:03 PM
Reviewer: System Administrator
Owner: System Administrator