OrDB
Neuron
  Data
Cochlea hair inner GLU cell
 Neuronal Receptors (1)
  
SN Property present CF-Compartment Receptor Connect Note Publication facts
1 Yes Distal equivalent dendrite Mechanoreceptors Stretch activated channels
 Neuronal Currents (5)
  
SN Property present CF-Compartment Current Connect Note Publication facts
1 Yes Soma I K Whole-cell patch-clamp recordings were used to identify and characterize ionic currents in isolated cells. Most cells possessed a slowly activating IK, which is approximately 80% inactive at rest. In a small subset of cells, IK was replaced by an IA. It is suggested that the kinetic properties of the ionic currents argue against electrical tuning
2 Yes Soma I h Whole-cell patch-clamp recordings were used to identify and characterize ionic currents in isolated cells. Most cells possessed an Ih, which actively contributed to the resting potential
3 Yes Soma I K,Ca Whole-cell patch-clamp recordings showed that variations in the kinetics of the outward current contribute substantially to the determination of resonant frequency
4 Yes Soma I Calcium The effects of intracellular calcium buffering on electrical tuning were studied in hair cells at apical and basal cochlear locations tuned to 100 and 300 Hz. Ca2+ imaging revealed about twice as many hotspots of Ca2+ entry during depolarization in high-frequency compared to low-frequency hair cells. It is suggested that each KCa channel is gated by Ca2+ entry through a few nearby Ca2+ channels, and that Ca2+ and KCa channels occupy, at constant channel density, a greater fraction of the membrane area in high-frequency cells than in low-frequency cells
5 Yes Soma I A Whole-cell patch-clamp recordings were used to identify and characterize ionic currents in isolated cells. In a small subset of cells, the IK was replaced by an IA. It is suggested that the kinetic properties of the ionic currents argue against electrical tuning
 Neuronal Transmitters (1)
  
SN Property present CF-Compartment transmitter Connect Note Publication facts
1 Yes Soma Glutamate
Other categories referring to Cochlea hair inner GLU cell
Neuronal Structure.Neurons   (1)
Revisions: 3
Last Time: 2/12/2018 2:46:07 PM
Reviewer: System Administrator
Owner: System Administrator