True

• Hippocampus CA1 pyramidal GLU cell Show Other

• Proximal apical dendrite Show Other

• I T low threshold Show Other

• Patch recordings yield an approximate channel density of 7 pS/micron^2 in juvenile rats < 4 wks of age, rising to 10 pS/micron^2 in older rats. Ca channel density was similar in other dendritic compartments, and in general lower than Na channel density Show Other
• However, in a few apical patches the channel density was increased X 3, which could indicate channel clustering. Ca fluorescence imaging shows that application of T-channel antagonists reduces the Ca influx associated with backpropagating action potentials, and has a two-fold greater effect in the dendrites than in the soma Show Other