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The baskets formed by inhibitory basket cells have high concentrations of glutamic acid decarboxylase (GAD), the enzyme that synthesizes GABA Show
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A 40-50% reduction in a small fraction of (peri-) somatic synapses with large or complex postsynaptic structure after kindling has been found. This functionally relevant reduction may be related to the loss of a specific class of interneurons, and could underlie the enhanced seizure susceptibility after kindling epileptogenesis Show
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