True

• Hippocampus CA3 pyramidal GLU cell Show Other

• Soma Show Other

• GabaA Show Other

• Intracellular recording from organotypic rat hippocampal cultures have shown that approximately 25% of single spikes in CA3 pyramidal neurons are followed by IPSPs at a fixed latency, presumeably a result of feedback inhibition from inhibitory interneurons. The addition of bicuculline (a competitive GABA(A) antagonist) completely abolished these responses, but they were insensitive to CGP35348, a GABA(B) antagonist Show Other
• There is also evidence that Zn+ can modulate bicuculline-sensitive responses to GABA early in development in rat (studied less than 8 days old) Show Other