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NMDA receptors play a critical role in dendrodendritic inhibition between mitral and granule cells. Moreover, N- and P/Q type calcium channels are involved. Show
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Calcium influx through NMDA receptors can directly trigger presynatic GABA release for local dendrodendritic feedback inhibition. DDI is elicited by photorelease of caged Ca++, with and without Cd++ and Ni++. Show
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Calcium influx through NMDA receptors directly evokes GABA release in granule cells. Show
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NMDA receptor is required for DDI (dendrodendritic inhibition) since IPSC was completely blocked by AP-5. Ineffectiveness of AMPA receptor-mediated EPSPs to activate the granule cells may be due to their intrinsic membrane properties. Show
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