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Substantia nigra pars reticulata principal GABA cell Show
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subthalamonigral input
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In vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity Show
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The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors [mGluR1 and mGluR5]” Reviewed in Show
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