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Types and distribution of voltage-gated K+ channels in the soma and apical dendrites were studied in acute brain slices Show
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The amplitude of ensemble K+ currents in cell-attached patches decreased along the apical dendrite as the distance from the soma increased, with a slope of -0.9 +/- 0.3 pA per 100um. In nucleated outside-out patches from soma in acute slices of sensorimotor cortex from 13- to 15-day-old Wistar rats some patches contained only I-A-like channels, other contained only IK-like channels that did not inactivate or inactivated slowly, and the remainder contained mixtures of both types. The amount of IA and IK depended weakly on distance along the primary apical dendrite from the soma. The amplitude of IA increased, while the amplitude of IK decreased Show
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