True

• Hippocampus CA1 pyramidal GLU cell Show Other

• Soma Show Other

• I h Show Other

• Depolarizing "sag" during larger hyperpolarizing voltage transients is indicative of Ih current in determinating the passive membrane properties of CA1 pyramidal neurons Show Other
• Membrane patches recorded in the cell-attached patch configuration from the soma and apical dendrites revealed an Ih that increased over sixfold from soma to distal dendrites. Ih demonstrated a mixed Na+-K+ conductance and was sensitive to low concentrations of external CsCl. As a result of Ih the propagation of subthreshold voltage transients is directionally specific.The elevated dendritic Ih density decreases EPSP amplitude and duration and reduces the time window over which temporal summation takes place Show Other