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Using conventional or perforated-patch whole cell recordings, SNc neurons acutely dissociated from P4 to P16 rats NMDA (100 nM, V(hold) = -60 mV) evoked inward, APV-sensitive currents (56.4 +/- 8.6 pA) in all tested neurons (n = 29). Strong depolarizing responses were observed under current-clamp Show
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The functional properties of NMDA receptors were studied in acute slices. Little variability in functional properties was found in different types of basal ganglia neurons Show
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